Robert T Dauchy Selected Research

13-hydroxy-9,11-octadecadienoic acid

4/2012	A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats.
10/2011	Circadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night.
9/2011	Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer.
12/2009	Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women.
8/2009	Antineoplastic effects of melatonin on a rare malignancy of mesenchymal origin: melatonin receptor-mediated inhibition of signal transduction, linoleic acid metabolism and growth in tissue-isolated human leiomyosarcoma xenografts.
10/2007	Dietary factors and growth and metabolism in experimental tumors.
5/2006	Human cancer xenograft perfusion in situ in rats: a new perfusion system that minimizes delivery time and maintains normal tissue physiology and responsiveness to growth-inhibitory agents.
1/2006	Dietary fish oil deactivates a growth-promoting signaling pathway in hepatoma 7288CTC in Buffalo rats.
12/2005	Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats.
9/2005	Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway.

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Robert T Dauchy Research Topics

Disease

34	Neoplasms (Cancer) 09/2021 - 02/2002
19	Breast Neoplasms (Breast Cancer) 09/2019 - 07/2002
7	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 07/2002
4	Neoplasm Metastasis (Metastasis) 11/2016 - 11/2012
3	Carcinogenesis 09/2021 - 06/2003
3	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 11/2013
3	Obesity 02/2018 - 05/2003
2	Leiomyosarcoma 03/2016 - 08/2009
2	Genomic Instability 06/2015 - 07/2014
1	Anhedonia 09/2021
1	Squamous Cell Carcinoma of Head and Neck 01/2021
1	Pathologic Complete Response 09/2019
1	Type 2 Diabetes Mellitus (MODY) 02/2018
1	Experimental Liver Neoplasms 01/2018
1	Body Weight Changes 01/2016
1	Hyperglycemia 01/2014
1	Hyperinsulinism (Hyperinsulinemia) 01/2014
1	Inflammation (Inflammations) 11/2013
1	Sarcoma (Soft Tissue Sarcoma) 08/2009
1	Squamous Cell Neoplasms (Squamous Cell Cancer) 08/2007
1	Lipoma (Lipomata) 01/2006

Drug/Important Bio-Agent (IBA)

28	MelatoninIBA 01/2021 - 02/2002
21	Linoleic Acid (Linoleate)IBA 01/2021 - 02/2002
16	13-hydroxy-9,11-octadecadienoic acidIBA 04/2012 - 02/2002
13	Fatty Acids (Saturated Fatty Acids)IBA 01/2016 - 07/2002
9	ThymidineIBA 01/2021 - 06/2004
8	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2004
7	Melatonin Receptors (Melatonin Receptor)IBA 10/2011 - 02/2002
6	Phosphotransferases (Kinase)IBA 09/2019 - 04/2012
5	Eicosapentaenoic AcidIBA 01/2021 - 04/2003
5	Messenger RNA (mRNA)IBA 09/2019 - 09/2011
5	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 05/2011 - 08/2004
5	Mitogen-Activated Protein KinasesIBA 05/2011 - 02/2002
5	Conjugated Linoleic AcidsIBA 08/2007 - 04/2003
4	Estrogen ReceptorsIBA 08/2014 - 09/2011
4	MitogensIBA 04/2012 - 06/2003
4	Biological ProductsIBA 12/2009 - 02/2002
4	Pertussis ToxinIBA 01/2006 - 06/2004
3	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021 - 04/2003
3	Transcription Factors (Transcription Factor)IBA 09/2019 - 08/2015
3	LipidsIBA 01/2014 - 05/2003
3	Steroid Receptors (Steroid Receptor)IBA 04/2011 - 06/2004
3	Corn Oil (Oil, Corn)IBA 08/2009 - 06/2004
3	Antineoplastic Agents (Antineoplastics)IBA 08/2009 - 02/2002
2	Fish OilsIBA 01/2021 - 01/2006
2	hydroxyoctadecadienoic acidIBA 01/2021 - 08/2004
2	MT1 Melatonin ReceptorIBA 09/2019 - 06/2015
2	Tamoxifen FDA LinkGeneric 09/2019 - 08/2014
2	Interleukin-6 (Interleukin 6)IBA 09/2019 - 11/2013
2	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2019 - 08/2015
2	Estrogen Receptor alphaIBA 08/2015 - 06/2015
2	Tyrosine (L-Tyrosine)FDA Link 08/2015 - 08/2014
2	Cytostatic AgentsIBA 06/2015 - 02/2002
2	Hormones (Hormone)IBA 01/2014 - 06/2004
2	Glycogen Synthase KinasesIBA 11/2012 - 05/2011
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2012 - 05/2011
2	Glucose (Dextrose)FDA LinkGeneric 04/2012 - 05/2011
2	Estrogens (Estrogen)FDA Link 10/2011 - 09/2011
2	Adenosine Monophosphate (AMP)IBA 10/2011 - 01/2006
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2011 - 04/2011
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2009 - 08/2007
2	Dietary Fats (Dietary Fat)IBA 10/2007 - 09/2005
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 10/2007 - 04/2003
2	AcidsIBA 08/2007 - 01/2006
2	GTP-Binding Proteins (G-Protein)IBA 01/2006 - 08/2004
2	ErbB Receptors (EGF Receptor)IBA 07/2002 - 02/2002
1	Anti-Anxiety Agents (Anxiolytics)IBA 09/2021
1	Sucrose (Saccharose)IBA 09/2021
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2021
1	Docosahexaenoic AcidsIBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 09/2019
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 09/2019
1	Sirtuin 1IBA 09/2019
1	MethyltransferasesIBA 09/2019
1	Pharmaceutical PreparationsIBA 09/2019
1	fascinIBA 11/2016
1	Retroelements (Retrotransposon)IBA 06/2015
1	Estrogen Receptor Modulators (Antiestrogen)IBA 08/2014
1	CarcinogensIBA 07/2014
1	Insulin-Like PeptidesIBA 11/2013
1	Insulin (Novolin)FDA Link 11/2013
1	Interleukin-17 (Interleukin 17)IBA 11/2013
1	EnzymesIBA 11/2012
1	CateninsIBA 11/2012
1	Lactic Acid (Lactate)FDA LinkGeneric 04/2012
1	Phospholipids (Phosphatides)FDA LinkGeneric 05/2011
1	Cholesterol Esters (Cholesteryl Esters)IBA 05/2011
1	Nonesterified Fatty Acids (NEFA)IBA 05/2011
1	Triglycerides (Triacylglycerol)IBA 05/2011
1	Histones (Histone)IBA 05/2011
1	Insulin-Like Growth Factor I (IGF-1)IBA 04/2011
1	Drinking WaterIBA 08/2009
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2007
1	Linoleic AcidsIBA 08/2007
1	Olive OilIBA 01/2006
1	Trans Fatty AcidsIBA 08/2004

Therapy/Procedure

5	Therapeutics 09/2019 - 02/2002
1	Drug Therapy (Chemotherapy) 08/2015
1	Operative Surgical Procedures 04/2012
1	Catheters 05/2006